UAS regulatory sequences drive expression of an inverted repeat.
circadian rhythm defective, with Scer\GAL4P2.4.Pdf
circadian rhythm defective | heat sensitive, with Scer\GAL4tim.PE, Scer\GAL80Pdf.PS
Scer\GAL4da.Switch.PT ActβJF03276 adults, fed with RU486 to activate expression, show no significant difference in lifespan compared to controls.
Down-regulation of Actβ in Pdf-positive neurons, through expression of ActβJF03276 under the control of Scer\GAL4P2.4.Pdf induces mild locomotor arrhythmicity. Expression of ActβJF03276 under the control of Scer\GAL4tim.PE and suppressed in Pdf-positive cells through the presence of Scer\GAL80Pdf.PS results in some rescue of the arrhythmic phenotype.