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General Information
Symbol
Dmel\Lfee
Species
D. melanogaster
Name
freaky eye
FlyBase ID
FBal0242925
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Most Lfee adult eyes are smaller than wildtype. The eyes have a nick at the anterior border of the eye, and often extra hairs and rod-like tissue are observed in this region. Overgrowth of eye tissue is occasionally observed.

Lfee/Lrev6-3 trans-heterozygotes have smaller eyes than Lfee alone.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

Lfee has size defective phenotype, suppressible by os[+]/upd11

Lfee has visible phenotype, suppressible by Df(1)os1/+

NOT suppressed by
Statement
Reference

Lfee has size defective phenotype, non-suppressible by hh[+]/hhbar3

Phenotype Manifest In
Enhanced by
Statement
Reference

Lfee has eye phenotype, enhanceable by Scer\GAL4ey.PH/upd1UAS.cZa

Lfee has eye phenotype, enhanceable by S6k[+]/S6k07084

Suppressed by
Statement
Reference

Lfee has eye phenotype, suppressible by os[+]/upd11

Lfee has eye phenotype, suppressible by MycUAS.cZa/Scer\GAL4ey.PH

Lfee has eye phenotype, suppressible by Df(1)os1/+

Lfee has eye phenotype, suppressible by Stat92EF/Stat92E06346

Lfee has eye phenotype, suppressible by domeΔCYT.UAS/Scer\GAL4ey.PH

NOT suppressed by
Statement
Reference

Lfee has eye phenotype, non-suppressible by Scer\GAL4ey.PH/CycEUAS.cLa

Lfee has eye phenotype, non-suppressible by hh[+]/hhbar3

Additional Comments
Genetic Interactions
Statement
Reference

Eye size is restored in Df(1)os1/+; Lfee animals.

Eye size is almost restored to normal in Lfee; Stat92E06346/Stat92EF animals.

Expression of domeΔCYT.Scer\UAS under the control of Scer\GAL4ey.PH in a Lfee mutant background restores eye size to normal.

Expression of upd1Scer\UAS.cZa under the control of Scer\GAL4ey.PH in a Lfee mutant background exacerbates the Lfee phenotype, resulting in eyeless heads.

Expression of CycEScer\UAS.cLa under the control of Scer\GAL4ey.PH in a Lfee mutant background does not restore eye size.

Expression of TorWT.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ey.PH in a Lfee background enhances the reduction in eye size observed in Lfee animals.

Lfee; S6k07084/+ flies have a reduced eye size compared to Lfee flies.

Expression of dmScer\UAS.cZa under the control of Scer\GAL4ey.PH in a Lfee background significantly restores eye size.

The reduced eye size of Lfee flies is not restored by hhbar3/+.

Xenogenetic Interactions
Statement
Reference

Expression of Hsap\CDKN1AScer\UAS.cHa under the control of Scer\GAL4ey.PH in a Lfee mutant background does not restore eye size, and flies have small eyes.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)