Allele Dmel\Acsl^{Scer\UAS.715.C.T:Hsap\MYC}

General Information
Symbol	Dmel\Acsl^{Scer\UAS.715.C.T:Hsap\MYC}	Species	D. melanogaster
Name		FlyBase ID	FBal0242928
Feature type	allele	Associated gene	Dmel\Acsl

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Zhang et al., 2009) in vitro construct - regulatory fusion (Zhang et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS sequences drive expression of the 715 amino acid Acsl isoform plus a C-terminal 6x T:Hsap\MYC tag. (Zhang et al., 2009)
Carried in construct	P{UAS-Acsl.715.MycC} (Zhang et al., 2009)
Tagged with	T:Hsap\MYC (Zhang et al., 2009)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Neutral lipid accumulation is increased in the posterior compartment of Scer\GAL4[en-e16E], Acsl[Scer\UAS.715.T:Hsap\MYC.C] wings discs. (Zhang et al., 2009)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Acsl^{Scer\UAS.715.C.T:Hsap\MYC}/Scer\GAL4^tub.PU rescues Acsl⁸/Acsl^k10313 (Zhang et al., 2009) Acsl^{Scer\UAS.715.C.T:Hsap\MYC}/Scer\GAL4^tub.PU rescues Acsl⁰⁵⁸⁴⁷/Acsl⁸ (Zhang et al., 2009)
Partially rescues	Acsl^{Scer\UAS.715.C.T:Hsap\MYC}/Scer\GAL4^tub.PU partially rescues Acsl¹/Acsl⁸ (Zhang et al., 2009) Acsl^{Scer\UAS.715.C.T:Hsap\MYC}/Scer\GAL4^tub.PU partially rescues Acsl⁰⁵⁸⁴⁷/Acsl⁸ (Zhang et al., 2009)
Fails to rescue	Acsl^{Scer\UAS.715.C.T:Hsap\MYC}/Scer\GAL4^dpp.blk1 fails to rescue Acsl⁸/Acsl^k10313 (Zhang et al., 2009)
Comments	Expression of Acsl[Scer\UAS.715.T:Hsap\MYC.C] under the control of Scer\GAL4[tub] partially rescues the lethality associated with the Acsl[8]/Acsl[1] and Acsl[8]/Acsl[05847] genotypes. Expression of Acsl[Scer\UAS.715.T:Hsap\MYC.C] under the control of Scer\GAL4[tub] restores neutral lipid staining in Acsl[8]/Acsl[05847] wing discs. Expression of Acsl[Scer\UAS.715.T:Hsap\MYC.C] under the control of Scer\GAL4[tub] restores well-ordered axon projection in the optic lamina of the third instar larval brain of Acsl[8]/Acsl[k10313] mutants. Expression of Acsl[Scer\UAS.715.T:Hsap\MYC.C] under the control of Scer\GAL4[dpp.blk1] fails to restore well-ordered axon projection in the optic lamina of the third instar larval brain of Acsl[8]/Acsl[k10313] mutants. (Zhang et al., 2009)
Stocks ( 1 )
Bloomington	32330 w^*; P{PZ}Acsl⁰⁵⁸⁴⁷/CyO, P{GAL4-Kr.C}DC3, P{UAS-GFP.S65T}DC7; P{UAS-Acsl.715.MycC}3/TM6B, Tb¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Acsl^{Scer\UAS.715.C.T:Hsap\MYC} Acsl^{Scer\UAS.715.T:Hsap\MYC.C}
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Zhang et al., 2009, Hum. Mol. Genet. 18(20): 3894--3905 Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain. [FBrf0209077]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Allele Dmel\AcslScer\UAS.715.C.T:Hsap\MYC

Allele Dmel\Acsl^{Scer\UAS.715.C.T:Hsap\MYC}