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General Information
Symbol
Dmel\mir-ban12
Species
D. melanogaster
Name
FlyBase ID
FBal0243239
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
ban12
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

~6kb deletion resulting from the imprecise excision of the P{EP}ban[EP3622] insertion(s). The deletion coordinates were reported as ~639230-645339.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Has an approximately 6kb deletion including the ban core sequence.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

ban12 mutant female germline stem cell clones are lost more rapidly than controls.

Heterozygous ban12 has no effect on eye morphology.

In 84% of 3rd instar larval gonads from ban12 mutants, and 75% of ban12/Df(3L)emc-E12, primordial germ cell clusters are marked with branched fusomes that are not seen in controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhancer of
Other
Additional Comments
Genetic Interactions
Statement
Reference

7.7% of ban12/Fmr1Δ50M double heterozygous adult females are fertile, and 4.6% ban12/Fmr1Δ113M are fertile. Double heterozygous adult females of ban12/Fmr1Δ113M or ban12/Fmr1Δ50M display a significant increase in the number of germaria with one or no germline stem cells, compared to controls, that progressively worsens from day 2 post-eclosion to day 12.

Xenogenetic Interactions
Statement
Reference

One copy of ban12 has no effect on the fused ommatidia phenotype seen when Avic\GFPFmr1.CGG90.E.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Complementation and Rescue Data
Comments

The lethal phenotype of ban12/Df(3L)emc-E12 is rescued with the introduction of ban+t7.2.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)