Open Close
General Information
Symbol
Dmel\Srpk79DVN100
Species
D. melanogaster
Name
FlyBase ID
FBal0243483
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Srpk79DVN
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
complex substitution
Comment:

3861 bp deletion resulting from the imprecise excision of P{lacW}srpk79DP1, which removes the transcription and translation starts of many of the srpk79D transcripts and the first 85 amino acids of the SR kinase domain. 23 bp of the P element remain at the site of the excision.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

An imprecise excision retaining 23 bp of the progenitor P{lacW}srpk79DP1 that deletes 3861 bp of the srpk79D locus downstream of the progenitor insertion site.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

General axonal transport and basic synaptic structure and function appear intact in srpk79DVN100 mutants.

srpk79DVN100 mutant larval nerves display larger and more numerous electron-dense ribbon structures resembling T-bars of presynaptic neuromuscular boutons than wild-type controls.

srpk79DVN100 mutant flies display flight impairment, reduced ability or motivation to walk on a horizontal surface, as well as reduced life span.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Srpk79DVN100
srpk79DVN100
Name Synonyms
Secondary FlyBase IDs
    References (3)