Allele Dmel\srpk79D^VN100

General Information
Symbol	Dmel\srpk79D^VN100	Species	D. melanogaster
Name		FlyBase ID	FBal0243483
Feature type	allele	Associated gene	Dmel\srpk79D

Allele class
Mutagen	Delta2-3
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	Delta2-3 (Nieratschker et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{lacW}srpk79D^P1 (Nieratschker et al., 2009)
Nature of the lesion	Statement Reference An imprecise excision retaining 23 bp of the progenitor P{lacW}srpk79D[P1] that deletes 3861 bp of the srpk79D locus downstream of the progenitor insertion site. (Nieratschker et al., 2009)
Cytology
Phenotypic Data
Phenotypic Class
	flight defective \| recessive (Nieratschker et al., 2009) locomotor behavior defective \| recessive (Nieratschker et al., 2009) neuroanatomy defective \| recessive (Nieratschker et al., 2009) short lived \| recessive (Nieratschker et al., 2009)
Phenotype Manifest In
	neuron \| larval stage (Nieratschker et al., 2009)
Detailed Description
	Statement Reference General axonal transport and basic synaptic structure and function appear intact in srpk79D[VN100] mutants. srpk79D[VN100] mutant larval nerves display larger and more numerous electron-dense ribbon structures resembling T-bars of presynaptic neuromuscular boutons than wild-type controls. srpk79D[VN100] mutant flies display flight impairment, reduced ability or motivation to walk on a horizontal surface, as well as reduced life span. (Nieratschker et al., 2009)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	srpk79D^VN100 (Johnson et al., 2009) Srpk79D^VN (Nieratschker et al., 2009)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Johnson et al., 2009, PLoS Biol. 7(9): e1000193 Negative regulation of active zone assembly by a newly identified SR protein kinase. [FBrf0208771] Nieratschker et al., 2009, PLoS Genet. 5(10): e1000700 Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila. [FBrf0208928]

Allele Dmel\srpk79DVN100

Allele Dmel\srpk79D^VN100