FlyBase Allele Report: Dmel\Hsp23[UAS.cKa]

General Information

Symbol

Dmel\Hsp23^UAS.cKa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Kazemi-Esfarjani

FlyBase ID

FBal0243511

Feature type

allele

Associated gene

Dmel\Hsp23

Associated Insertion(s)

Carried in Construct

P{UAS-Hsp23.K}

Also Known As

UAS-Hsp23

Key Links

Transgenic product class

wild_type

(Kazemi-Esfarjani, 2010.5.11)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Kazemi-Esfarjani, 2010.5.11)

Mutagen

in vitro construct

(Kazemi-Esfarjani, 2010.5.11)

Progenitor genotype

Carried in construct

P{UAS-Hsp23.K}

Cytology

Description

UAS regulatory sequences drive expression of Hsp23.

(Kazemi-Esfarjani, 2010.5.11)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsp23

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

presynaptic active zone | decreased number | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has presynaptic active zone | third instar larval stage | increased number phenotype, non-enhanceable by pkm^KK110542, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-enhanceable by pkm^KK110542, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

NOT suppressed by

Statement

Reference

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has presynaptic active zone | increased number | third instar larval stage phenotype, non-suppressible by pkm^KK110542, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by pkm^KK110542, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Enhancer of

Statement

Reference

Hsp23^UAS.cKa/Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 is an enhancer of presynaptic active zone | third instar larval stage | increased number phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

Hsp23^UAS.cKa/Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 is an enhancer of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

NOT Enhancer of

Statement

Reference

Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42 is a non-enhancer of presynaptic active zone | third instar larval stage | increased number phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42 is a non-enhancer of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

NOT Suppressor of

Statement

Reference

Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42 is a non-suppressor of presynaptic active zone | increased number | third instar larval stage phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42 is a non-suppressor of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Scer\GAL4^Toll-6-D42, pkm^KK110542

(Santana et al., 2020)

Other

Statement

Reference

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has embryonic/larval neuromuscular junction | third instar larval stage phenotype

(Santana et al., 2020)

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has larval ventral nerve cord | third instar larval stage phenotype

(Santana et al., 2020)

Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42 has presynaptic active zone | increased number | third instar larval stage phenotype

(Santana et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Hsp23^UAS.cKa and Hsp26^{UAS.ORF.Tag:HA} under the control of Scer\GAL4^Toll-6-D42 leads to increase in the neuronal activity of ventral nerve cord of third instar larvae.

(Santana et al., 2020)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

30541

w¹¹¹⁸; P{UAS-Hsp23.K}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Hsp23^Scer\UAS.cKa

Hsp23^UAS.cKa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Kazemi-Esfarjani

Secondary FlyBase IDs

References (6)

Report Sections

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