FlyBase Allele Report: Dmel\sano[UAS.cCa]

General Information

Symbol

Dmel\sano^UAS.cCa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Chung

FlyBase ID

FBal0243787

Feature type

allele

Associated gene

Dmel\sano

Associated Insertion(s)

Carried in Construct

P{UAS-sano.C}

Key Links

Transgenic product class

wild_type

(Chung et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Chung et al., 2009)

Mutagen

in vitro construct

(Chung et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-sano.C}

Cytology

Description

UASt regulatory sequences drive expression of the sano open reading frame.

(Chung et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

sano

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity, with Scer\GAL4^Bx-MS1096

(Chung et al., 2009)

abnormal planar polarity, with Scer\GAL4^hs.2sev

(Chung et al., 2009)

abnormal planar polarity, with Scer\GAL4^ptc-559.1

(Chung et al., 2009)

visible, with Scer\GAL4^Bx-MS1096

(Chung et al., 2009)

visible, with Scer\GAL4^ptc-559.1

(Chung et al., 2009)

Phenotype Manifest In

embryonic/larval tracheal dorsal trunk, with Scer\GAL4^btl.PS

(Chung et al., 2009)

eye photoreceptor cell, with Scer\GAL4^hs.2sev

(Chung et al., 2009)

first posterior wing cell, with Scer\GAL4^ptc-559.1

(Chung et al., 2009)

macrochaeta, with Scer\GAL4^Bx-MS1096

(Chung et al., 2009)

ommatidium, with Scer\GAL4^hs.2sev

(Chung et al., 2009)

wing, with Scer\GAL4^Bx-MS1096

(Chung et al., 2009)

wing hair, with Scer\GAL4^ptc-559.1

(Chung et al., 2009)

Detailed Description

Statement

Reference

Embryos expressing sano^Scer\UAS.cCa under the control of Scer\GAL4^btl.PS have shortened dorsal trunks.

Expression of sano^Scer\UAS.cCa under the control of Scer\GAL4^Bx-MS1096 results in misorientation of bristles in the adult thorax. These animals show a decrease in overall wing size.

Expression of sano^Scer\UAS.cCa under the control of Scer\GAL4^ptc-559.1 results in swirling wing hair patterns in the adult. The distance between wing veins L3 and L4 is reduced compared to wild type (this is not due to an effect on cell number).

Expression of sano^Scer\UAS.cCa under the control of Scer\GAL4^hs.2sev results in ommatidial polarity defects, including misoriented and symmetrical photoreceptor phenotypes, as well as abnormal photoreceptor numbers. Approximately 14.5% of the ommatidia show defects.

(Chung et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

sano^UAS.cCa/Scer\GAL4^btl.PS partially rescues sano^KO3

(Chung et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

sano^Scer\UAS.cCa

sano^UAS.cCa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Chung

Secondary FlyBase IDs

References (1)

Report Sections

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