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General Information
Symbol
Scer\GAL4c202a
Species
S. cerevisiae
Name
FlyBase ID
FBal0243980
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
L1-Gal4, c202a-GAL4, c202-GAL4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GAL4}c202a
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    Scer\GAL4c202a drives expression in laminar monopolar neuron L1 starting at 48 hours APF.

     
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Blocking neural transmission in Scer\GAL4c202a (L1)-expressing neurons results in defects in turning responses to rotational visual motion. The flies are virtually non-responsive to moving light edges (a transition from brighter to darker). Responses to dark edge motion are unaffected. In an opposing edge assay (in which light and dark edges move in opposite directions) the flies turn in the direction of the dark edge motion.

    When neurons expressing Scer\GAL4c202a (L1) and Scer\GAL421D (L2) are both silenced the flies do not respond to rotational stimuli.

    In contrast to silencing either neuron alone, when neurons expressing Scer\GAL4c202a (L1) and Scer\GAL40595 (L3) are both silenced the flies show little response to dark edge motion. In addition, these flies are largely unable to respond to rotating square wave gratings containing both edge types.

    Additionally silencing Scer\GAL40987 (L4)-expressing neurons does not enhance the defects in rotational visual motion response seen when Scer\GAL4c202a (L1)-expressing neurons are silenced.

    Blocking neural transmission in Scer\GAL4c202a (L1)-expressing neurons does not affect the modulation of forward walking speed in response to translational motion stimuli seen in controls.

    Additionally silencing Scer\GAL4c202a (L1)-expressing neurons does not enhance the defects in translational motion response seen when Scer\GAL421D (L2)-expressing neurons are silenced.

    Additionally silencing Scer\GAL4c202a (L1)-expressing neurons does not enhance the defects in translational motion response seen when Scer\GAL40595 (L3)-expressing neurons are silenced.

    Blocking neural transmission in both Scer\GAL4c202a (L1) and Scer\GAL40987 (L4)-expressing neurons does not result in defects in responses to translational motion stimuli.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Scer\GAL4c202a
    Name Synonyms
    Secondary FlyBase IDs
      References (18)