FB2025_01 , released February 20, 2025
Allele: Dmel\bazS980E.UASp.mGFP6
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General Information
Symbol
Dmel\bazS980E.UASp.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0243989
Feature type
allele
Associated gene
Dmel\baz
Associated Insertion(s)
Carried in Construct
P{UASp-baz.S980E.GFP}
Key Links
Transgenic product class
missense_variant
(Morais-de-Sá et al., 2010)
polypeptide_post_translational_processing_variant
(Morais-de-Sá et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Morais-de-Sá et al., 2010)
polypeptide_post_translational_processing_variant
(Morais-de-Sá et al., 2010)
Mutagen
in vitro construct
(Morais-de-Sá et al., 2010)
Progenitor genotype
Carried in construct
P{UASp-baz.S980E.GFP}
Cytology
Description

UASp regulatory sequences drive expression of a phosphomimetic form of baz (containing the S980E mutation) that is tagged with mGFP6.

(Morais-de-Sá et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
baz
Tagged with
mGFP6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of bazS980E.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 results in a defect in the localization of the oocyte nucleus. Eggs derived from these females show a high frequency of dorsal appendage defects.

      (Morais-de-Sá et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of bazS980E.Scer\UAS.P\T.T:Avic\GFP-m6 fails to rescue the abnormal centrosome positioning of embryos from mothers expressing aPKCHMS01320 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16.

      (Jiang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      bazS980E.UASp.mGFP6/Scer\GAL4Act5C.PI rescues baz4

      (Morais-de-Sá et al., 2010)

      bazS980E.UASp.mGFP6/Scer\GAL4VP16.mat.αTub67C rescues baz4

      (Morais-de-Sá et al., 2010)
      Comments

      Expression of bazS980E.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4Act5C.PI in clones in the follicular epithelium rescues the epithelial organisation defects seen in the follicle cells of baz4 females.

      The epithelial organisation defects seen in baz4 zygotic mutant embryos are rescued by zygotic expression of bazS980E.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16.

      (Morais-de-Sá et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bazS980E.Scer\UAS.P\T.T:Avic\GFP-m6
      bazS980E.UASp.mGFP6
      Name Synonyms
      Secondary FlyBase IDs
        References (2)