na^har is rescued by Scer\GAL4^Clk.1.5/na^UAS.cLa

na^har is rescued by Scer\GAL4^elav-C155/na^UAS.cLa

na^har is rescued by na^UAS.cLa/Scer\GAL4^Clk.8.0

na^har is rescued by Scer\GAL4^tim.PE/na^UAS.cLa

na^har is partially rescued by Scer\GAL4^Clk.1.5/na^UAS.cLa

na^har is partially rescued by Scer\GAL4^cry.PZ/na^UAS.cLa

na^har is partially rescued by na^UAS.cLa/Scer\GAL4^cry.PE

na^har is partially rescued by na^UAS.cLa/Scer\GAL4^Mai179

na^har is partially rescued by na^E.UAS/Scer\GAL4^Clk.8.0

na^har is not rescued by na^UAS.cLa/Scer\GAL4^P2.4.Pdf

na^har is not rescued by Scer\GAL4¹¹¹⁸/na^UAS.cLa

na^har is not rescued by Scer\GAL4^tim.PE/na^E.UAS

DN1[[P] rescue of na^har mutants through expression of na^Scer\UAS.cLa under the control of Scer\GAL4^Clk.4.1M restores only the acute responsiveness to lights-on (AMI), but not the sustained masking index.

Morning anticipatory behaviour is restored in na^har mutants where na^Scer\UAS.cLa is expressed under the control of Scer\GAL4^Clk.4.1M. However, evening behaviour under LD conditions is not rescued.

Expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^elav-C155, Scer\GAL4^Clk.8.0 or Scer\GAL4^tim.PE results in strong rescue of the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions, with rescue of evening anticipation, timing of morning anticipation and response to lights on.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^cry.PZ results in robust rescue of the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions.

Expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^P2.4.Pdf or Scer\GAL4¹¹¹⁸ fails to rescue the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions.

The rescue of the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions by expression of na^Scer\UAS.cLa under the control of Scer\GAL4^elav-C155 is almost completely blocked if the flies are also expressing Scer\GAL80^cry.PS.

The rescue of the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions by expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^elav-C155, Scer\GAL4^Clk.8.0 or Scer\GAL4^tim.PE is not strongly affected in the flies are also expressing Scer\GAL80^Pdf.PS.

Expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^cry.PE or Scer\GAL4^Mai179 partially rescues the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions; evening anticipation is rescued, but the lights-on activity response is not rescued. Morning anticipation is not affected if expression is driven by Scer\GAL4^Mai179, but if expression is driven by Scer\GAL4^cry.PE the degree of morning anticipation is suppressed compared to na^har mutant controls. Evening anticipation is still rescued in na^har expressing na^Scer\UAS.cLa under the control of Scer\GAL4^cry.PE that are also expressing Scer\GAL80^Pdf.PS.

Expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^elav-C155 or Scer\GAL4^Clk.8.0 significantly rescues the circadian locomotor activity defects seen in na^har flies under constant darkness conditions, with a rescue of both morning and evening peaks being seen.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^cry.PE partially rescues the circadian locomotor activity defects seen in na^har flies under constant darkness conditions; rescue of a single broad evening peak is seen, but there is either no morning anticipatory behaviour or it is very delayed and there are no reductions in midday activity compared to na^har mutant controls.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^Mai179 partially rescues the circadian locomotor activity defects seen in na^har flies under constant darkness conditions; there is a strong rescue of the evening activity peak and a reduction in midday activity, but there is no change in morning anticipatory behaviour compared to na^har mutant controls.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^tim.PE significantly rescues the circadian locomotor activity defects seen in na^har flies under constant darkness conditions.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^cry.PZ weakly rescues the circadian locomotor activity defects seen in na^har flies under constant darkness conditions; a higher proportion of flies with rhythmic behaviour is seen and the rescued flies show clear persistant morning and evening peaks.

Expression of na^Scer\UAS.cLa under the control of Scer\GAL4^P2.4.Pdf fails to rescue the circadian locomotor activity defects seen in na^har flies under constant darkness conditions.

The rescue of the circadian locomotor activity defects seen in na^har flies under constant darkness conditions by expression of na^Scer\UAS.cLa under the control of either Scer\GAL4^elav-C155, Scer\GAL4^Clk.8.0, Scer\GAL4^cry.PE or Scer\GAL4^tim.PE is reduced if the flies are also expressing Scer\GAL80^Pdf.PS.

Expression of na^E.Scer\UAS under the control of Scer\GAL4^tim.PE fails to rescue the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions.

Expression of na^E.Scer\UAS under the control of Scer\GAL4^Clk.8.0 partially rescues the circadian locomotor activity defects seen in na^har flies under 12 hour light/12 hour dark conditions; there is no rescue of the timing of morning anticipatory behaviour, but there is partial rescue of evening anticipation.

Expression of na^E.Scer\UAS under the control of Scer\GAL4^Clk.8.0 does not generally rescue the the circadian locomotor activity defects seen in na^har flies under constant darkness conditions.