FB2025_01 , released February 20, 2025
Allele: Dmel\Nup107mRFP1
Open Close
General Information
Symbol
Dmel\Nup107mRFP1
Species
D. melanogaster
Name
FlyBase ID
FBal0244138
Feature type
allele
Associated gene
Dmel\Nup107
Associated Insertion(s)
Carried in Construct
P{mRFP-Nup107.K}
Also Known As
mRFP-Nup107, RFP-Nup107WT, RFP::Nup107
Key Links
Transgenic product class
genomic_DNA
(Katsani et al., 2008)
wild_type
(Katsani et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Katsani et al., 2008)
wild_type
(Katsani et al., 2008)
Mutagen
in vitro construct
(Katsani et al., 2008)
Progenitor genotype
Carried in construct
P{mRFP-Nup107.K}
Cytology
Description

4.2kb XhoI-NsiI genomic fragment containing Nup107, including 1.5kb upstream and 0.kb downstream sequence. A mRFP1 tag has been inserted in-frame at an AgeI site located 18bp upstream of the ATG codon of Nup107.

(Katsani et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Nup107
Encoded product / tool
Nup107
Tagged with
mRFP1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      oogenesis
      follicle cell
      (Groen et al., 2015)
      Additional Information
      Statement
      Reference

      Nup107mRFP1 protein labels the nuclear envelope in follicle cells.

      (Groen et al., 2015)
       
      Marker for
      nuclear envelope
      (Groen et al., 2015)
      Reflects expression of
      Nup107
      (Groen et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Nup107mRFP1 rescues Nup107E8

      (Weinberg-Shukron et al., 2015)

      Nup107mRFP1 rescues Nup107E8

      (Katsani et al., 2008)
      Comments

      Expression of Nup107T:Disc\RFP-mRFP rescues the lethality of Nup107E8/Nup107E8 mutants, and results in no apparent morphological defects.

      (Weinberg-Shukron et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nup107T:Disc\RFP-mRFP
      Nup107mRFP1
      Name Synonyms
      Secondary FlyBase IDs
        References (12)