Allele Dmel\Spn77Ba^{Scer\UAS.P\T.T:Ivir\HA1}

General Information
Symbol	Dmel\Spn77Ba^{Scer\UAS.P\T.T:Ivir\HA1}	Species	D. melanogaster
Name		FlyBase ID	FBal0244343
Feature type	allele	Associated gene	Dmel\Spn77Ba

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Tang et al., 2008) in vitro construct - regulatory fusion (Tang et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory and P\T promoter sequences drive expression of the full length Spn77Ba open reading frame, which is tagged at the C-terminal end with T:Ivir\HA1. (Tang et al., 2008)
Carried in construct	P{UASp-Spn77Ba.HA} (Tang et al., 2008)
Tagged with	T:Ivir\HA1 (Tang et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Cuticle melanisation induced by B.bassiana is partially suppressed by expression of Spn77Ba[Scer\UAS.P\T.T:Ivir\HA1] under the control of Scer\GAL4[Act]. (Tang et al., 2008)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Spn77Ba^{Scer\UAS.P\T.T:Ivir\HA1}/Scer\GAL4^Act.PU rescues Spn77Ba^W7 (Tang et al., 2008)
Comments	Expression of Spn77Ba[Scer\UAS.P\T.T:Ivir\HA1] under the control of Scer\GAL4[hs.PB] at 18[o]C allows some Spn77Ba[W7] animals to grow to the second instar stage. These animals have melanised trachea and in most cases die before reaching the third instar stage. Expression of Spn77Ba[Scer\UAS.P\T.T:Ivir\HA1] under the control of Scer\GAL4[hs.PB] at 22-25[o]C allows some Spn77Ba[W7] animals to survive to the third larval instar or pupal stages. These larvae and pupae have melanised trachea. (Tang et al., 2008)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Spn77Ba^{Scer\UAS.P\T.T:Ivir\HA1}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Tang et al., 2008, Dev. Cell 15(4): 617--626 A serpin that regulates immune melanization in the respiratory system of Drosophila. [FBrf0206001]

Allele Dmel\Spn77BaScer\UAS.P\T.T:Ivir\HA1

Allele Dmel\Spn77Ba^{Scer\UAS.P\T.T:Ivir\HA1}