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General Information
Symbol
Dmel\kibraUASp.cYa
Species
D. melanogaster
Name
FlyBase ID
FBal0244408
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASp regulatory sequences drive expression of the kibra RE26350 cDNA clone.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of kibraScer\UAS.P\T.cYa under the control of Scer\GAL4nub-AC-62 leads to reduced size of adult wing blade.
Expression of kibraScer\UAS.P\T.cYa under the control of Scer\GAL4GMR.PF results in a reduction in the size of the adult eye.
Expression of kibraScer\UAS.P\T.cYa under the control of Scer\GAL4GMR.PF results in ectopic apoptosis in the eye imaginal disc and adults with smaller eyes than normal.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
The increased size of adult wing blade characteristic for flies expressing exKK100573 under the control of Scer\GAL4nub-AC-62 is suppressed by co-expression of kibraScer\UAS.P\T.cYa, which on its own leads to reduced adult wing size. The wing undergrowth observed in flies expressing kibraScer\UAS.P\T.cYa under the control of Scer\GAL4nub-AC-62 (their wing area is significantly decreased compared to controls) is further reduced by co-expression of crbGD14463 (which on its own leads to wing overgrowth).
Co-expression of kibraScer\UAS.P\T.cYa and ykiScer\UAS.cHa under the control of Scer\GAL4GMR.PF results in an eye size similar to that caused by expression of ykiScer\UAS.cHa alone under the control of Scer\GAL4GMR.PF. Homozygous savshrp-1 eyes (induced by the eyFLP method) that are also expressing kibraScer\UAS.P\T.cYa under the control of Scer\GAL4GMR.PF show overgrowth similar to that seen in eyes that are mutant for savshrp-1 alone. In the eye discs of these animals, the ectopic cell death that is induced by expression of kibraScer\UAS.P\T.cYa under the control of Scer\GAL4GMR.PF in a wild-type background is suppressed in the savshrp-1 clones.
Xenogenetic Interactions
Statement
Reference
The reduction in eye size caused by expression of kibraScer\UAS.P\T.cYa under the control of Scer\GAL4GMR.PF is significantly suppressed by co-expression of BacA\p35Scer\UAS.cHa.
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
kibraScer\UAS.P\T.cYa
kibraUASp.cYa
Name Synonyms
Secondary FlyBase IDs
    References (3)