Open Close
General Information
Symbol
Dmel\SG46SG46
Species
D. melanogaster
Name
FlyBase ID
FBal0244441
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference

SG46[+]/SG46SG46 is a suppressor of eye phenotype of DCTN1-p1501

Additional Comments
Genetic Interactions
Statement
Reference

SG46SG46 dominantly suppresses the eye phenotype caused by expression of GlΔ.Scer\UAS under the control of Scer\GAL4GMR.PF.

Both the lack of a terminal bend and the swollen axon tip phenotypes of giant fiber axons that are seen in adults expressing GlΔ.Scer\UAS under the control of Scer\GAL4A307 are suppressed by SG46SG46/+.

Heterozygosity for SG46SG46 partially suppresses the giant fiber system electrophysiological defects in animals expressing GlΔ.Scer\UAS under the control of Scer\GAL4A307; all preparations respond to brain stimulation and the response latency is shorter than in flies expressing GlΔ.Scer\UAS under the control of Scer\GAL4A307 in a wild-type background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

It has not been determined whether the lethality of the chromosome is caused by the mutation that modifies the eye phenotype caused by expression of GlΔ.Scer\UAS under the control of Scer\GAL4GMR.PF, so it is possible that the recessive lethality of the chromosome is due to a second-site mutation.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
SG46SG46
Name Synonyms
Secondary FlyBase IDs
    References (1)