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General Information
Symbol
Dmel\Mmp1Pro-pex.f1.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0244593
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the f1 isoform of Mmp1 carrying a deletion (amino acids 112-298) which removes the entire catalytic domain.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Very few third instar larvae expressing Mmp1E225A.f1.Scer\UAS under the control of Scer\GAL4αTub84B.PL display broken tracheal dorsal trunks. Almost all animals survive to pupariation. The majority of dissected pupae show defects in head eversion, and some animals show additional defects in wing eversion.

Very few Mmp1Q273stop/Mmp1W439stop transheterozygous mutant third instar larvae expressing Mmp1Pro-pex.f1.Scer\UAS under the control of Scer\GAL4αTub84B.PL display broken tracheal dorsal trunks. The majority of dissected pupae show defects in head eversion, and some animals show additional defects in wing eversion.

No third instar larvae expressing Mmp1Pro-pex.f1.Scer\UAS under the control of Scer\GAL4btl.PS display broken tracheal dorsal trunks.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of Mmp1Pro-pex.f1.Scer\UAS suppresses the bristle phenotype observed in flies expressing Mmp1f1.Scer\UAS under the control of Scer\GAL4dpp.PH.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Mmp1Pro-pex.f1.Scer\UAS
Mmp1Pro-pex.f1.UAS
Name Synonyms
Secondary FlyBase IDs
    References (2)