Allele Hsap\NRF1^elav.PH

General Information
Symbol	Hsap\NRF1^elav.PH	Species	H. sapiens
Name	embryonic lethal abnormal vision promoter construct of Haussmann	FlyBase ID	FBal0244704
Feature type	allele	Associated gene	Hsap\NRF1

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Haussmann et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference elav promoter sequences drive expression of the Hsap\NRF1 open reading frame and ewg 3'UTR sequences. (Haussmann et al., 2008)
Carried in construct	P{elav-NRF-1.H} (Haussmann et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Hsap\NRF1^elav.PH is a suppressor of lethal \| recessive \| embryonic stage phenotype of ewg² (Haussmann et al., 2008) Hsap\NRF1^elav.PH is a suppressor of neuroanatomy defective \| larval stage phenotype of ewg² (Haussmann et al., 2008)
Other
Statement Reference Hsap\NRF1^elav.PH, ewg² has lethal \| pharate adult stage phenotype (Haussmann et al., 2008)
Phenotype Manifest In
Suppressor of
Statement Reference Hsap\NRF1^elav.PH is a suppressor of embryonic/larval neuromuscular junction phenotype of ewg² (Haussmann et al., 2008) Hsap\NRF1^elav.PH is a suppressor of NMJ bouton phenotype of ewg² (Haussmann et al., 2008)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference The increase in bouton number seen at the larval neuromuscular junctions of ewg[2] motorneurons is completely rescued by Hsap\NRF1[elav.PH]. ewg[2] animals expressing Hsap\NRF1[elav.PH] develop to pharate adults, but fail to hatch. (Haussmann et al., 2008)
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Hsap\NRF1^elav.PH
Name Synonym	embryonic lethal abnormal vision promoter construct of Haussmann
Secondary FlyBase IDs

References ( 1 )
Research paper	Haussmann et al., 2008, Genome Biol. 9(4): R73 Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. [FBrf0209726]

Allele Hsap\NRF1elav.PH

Allele Hsap\NRF1^elav.PH