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General Information
Symbol
Dmel\kibra1
Species
D. melanogaster
Name
FlyBase ID
FBal0244819
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor insertion, resulting in a deletion which removes the first exon (this includes the translation start site).

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Statement
Reference

kibra1/kibra02404 has lethal | pupal stage phenotype, suppressible by yki[+]/ykiB5

Other
Phenotype Manifest In
Enhanced by
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

Pupae with mosaic heads that are largely doubly mutant for exe1/exe1 and kibra1/kibra3 (clones induced using the eyFLP method without cell lethal) do not eclose and normal head structures are displaced by overgrown tissue.

Expression of exGD12782 under the control of Scer\GAL4GMR.PF severely enhances the eye overgrowth phenotype of homozygous kibra1 eyes (generated using the eyFLP method).

Expression of MerGD1484 under the control of Scer\GAL4GMR.PF enhances the eye overgrowth phenotype of homozygous kibra1 eyes (generated using the eyFLP method).

exe1 kibra1 double mutant clones in the eye imaginal disc are very large and invariably adopt a rounded shape.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)