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General Information
Symbol
Dmel\kibra3
Species
D. melanogaster
Name
FlyBase ID
FBal0244821
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G14723571A

Reported nucleotide change:

G?A

Amino acid change:

M1I | kibra-PA; M1I | kibra-PB

Reported amino acid change:

M1I

Comment:

Generated through reversion mutagenesis of the line carrying P{EPgy2}kibraEY03746.

transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Point mutation in the kibra start codon (ATG to ATA). The P{EPgy2}EY03746 insertion present in the progenitor is still present.

Insertion components
P{EPgy2}EY03746
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Phenotype Manifest In
Other
Additional Comments
Genetic Interactions
Statement
Reference

Pupae with mosaic heads that are largely doubly mutant for exe1/exe1 and kibra1/kibra3 (clones induced using the eyFLP method without cell lethal) do not eclose and normal head structures are displaced by overgrown tissue.

Eyes doubly homozygous for Mer4 and kibra3 (generated using the eyFLP method) show stronger overgrowth than eyes singly homozygous for Mer4.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

kibra3 was selected as a mutation that reverts the kibraEY03746 phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)