FlyBase Allele Report: Dmel\Egfr[JF01083]

General Information

Symbol

Dmel\Egfr^JF01083

Species

D. melanogaster

Name

FlyBase ID

FBal0245403

Feature type

allele

Associated gene

Dmel\Egfr

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01083}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

(Ni et al., 2008)

Progenitor genotype

Carried in construct

P{TRiP.JF01083}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01083

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | adult stage, with Scer\GAL4^en-e16E

(Ni et al., 2008)

visible | adult stage, with Scer\GAL4^GMR.PU

(Khare et al., 2017)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Khare et al., 2017)

wing, with Scer\GAL4^en-e16E

(Ni et al., 2008)

wing vein, with Scer\GAL4^dpp.PU

(Khare et al., 2017)

wing vein, with Scer\GAL4^en-e16E

(Ni et al., 2008)

Detailed Description

Statement

Reference

Expressing Egfr^JF01083 under the control of Scer\GAL4^GMR.PU leads to a rough eye phenotype.

Scer\GAL4^dpp.PU-driven expression leads to wing vein defects.

(Khare et al., 2017)

Expression of Egfr^JF01083 under the control of Scer\GAL4^en-e16E results in defects in wing growth and vein formation. The phenotype is more severe in males than females.

(Ni et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Egfr^JF01083, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by Hsap\KCNC3^R423H.UAS, Scer\GAL4^GMR.PU

(Khare et al., 2017)

Enhancer of

Statement

Reference

Egfr^JF01083, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of Hsap\KCNC3^R423H.UAS, Scer\GAL4^GMR.PU

(Khare et al., 2017)

Phenotype Manifest In

Enhanced by

Statement

Reference

Egfr^JF01083, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Hsap\KCNC3^R423H.UAS, Scer\GAL4^GMR.PU

(Khare et al., 2017)

Egfr^JF01083, Scer\GAL4^dpp.PU has wing vein phenotype, enhanceable by Hsap\KCNC3^R423H.UAS, Scer\GAL4^dpp.PU

(Khare et al., 2017)

Enhancer of

Statement

Reference

Egfr^JF01083, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\KCNC3^R423H.UAS, Scer\GAL4^GMR.PU

(Khare et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

31525

y¹ v¹; P{TRiP.JF01083}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Egfr^JF01083

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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