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General Information
Symbol
Dmel\Tsc1JF01262
Species
D. melanogaster
Name
FlyBase ID
FBal0245554
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing Tsc1JF01262 under the control of Scer\GAL4elav.Switch.PO or Scer\GAL4Mef2.247.Switch (and feeding with RU486 to induce expression via the GeneSwitch system) do not exhibit defective learning in an aversive conditioning assay, but do exhibit defects in a reversal-learning paradigm, with a third-odor preference assay showing an inability to forget the first aversive odor association after training with a second aversive odor, as compared to controls.

Expression of Tsc1JF01262 in cardiac muscle under the control of Scer\GAL4GMR88D05 has no effect on pupal eclosion rates.

Expression of Tsc1JF01262 in skeletal muscle under the control of Scer\GAL4how-24B has no effect on pupal eclosion rates.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Tsc1JF01262 does not suppress the enlarged bouton phenotype seen when Vap-33AP58S.cRa.Scer\UAS is expressed under the control of Scer\GAL4elav-C155.

Co-expression of Tsc1Scer\UAS.cTa and gigScer\UAS.cTa does not suppress the small bouton phenotype seen when Vap-33AScer\UAS.cRa is expressed under the control of Scer\GAL4elav-C155.

Expression of Tsc1JF01262 suppresses the small bouton phenotype seen when Vap-33AScer\UAS.cRa is expressed under the control of Scer\GAL4elav-C155.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Tsc1JF01262
Name Synonyms
Secondary FlyBase IDs
    References (6)