FlyBase Allele Report: Dmel\gpp[JF01283]

General Information

Symbol

Dmel\gpp^JF01283

Species

D. melanogaster

Name

FlyBase ID

FBal0245575

Feature type

allele

Associated gene

Dmel\gpp

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01283}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

(Ni et al., 2008)

Progenitor genotype

Carried in construct

P{TRiP.JF01283}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01283

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by Rbf^HMS03004

(Parkhitko et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^Act5C.PI

(Dietz et al., 2015)

viable, with Scer\GAL4^da.G32

(Nil et al., 2023)

viable, with Scer\GAL4^en-e16E

(Nil et al., 2023)

visible | adult stage, with Scer\GAL4^en.PU

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^en-e16E

(Nil et al., 2023)

visible | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^GMR.PF

(Dietz et al., 2015)

Phenotype Manifest In

crossvein, with Scer\GAL4^en-e16E

(Nil et al., 2023)

eye, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

eye, with Scer\GAL4^GMR.PF

(Dietz et al., 2015)

posterior crossvein, with Scer\GAL4^en.PU

(Dietz et al., 2015)

wing, with Scer\GAL4^en.PU

(Dietz et al., 2015)

wing vein, with Scer\GAL4^en.PU

(Dietz et al., 2015)

Detailed Description

Statement

Reference

Expression of gpp^JF01283 results in: rough eye phenotype (with either Scer\GAL4^ey.PH or Scer\GAL4^GMR.PF), ectopic veins or missing posterior crossvein (with Scer\GAL4^en.PU) and lethality (with Scer\GAL4^Act5C.PI). No overt adult phenotype is observed with the Scer\GAL4^nub.PK driver.

(Dietz et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, gpp^JF01283 has visible | adult stage phenotype, enhanceable by Scer\GAL4^en.PU/htt^GD14943

(Dietz et al., 2015)

Scer\GAL4^en.PU, gpp^JF01283 has visible | adult stage phenotype, enhanceable by htt^int

(Dietz et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, gpp^JF01283 has wing phenotype, enhanceable by Scer\GAL4^en.PU/htt^GD14943

(Dietz et al., 2015)

Scer\GAL4^en.PU, gpp^JF01283 has wing phenotype, enhanceable by htt^int

(Dietz et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The adult wing phenotype induced by expression of gpp^JF01283 under the control of Scer\GAL4^en.PU is enhanced by co-expression of htt^GD14943 or by combination with a single copy of htt^int.

(Dietz et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

31481

y¹ v¹; P{TRiP.JF01283}attP2/TM3, Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

gpp^JF01283

(Dietz et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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