FB2025_01 , released February 20, 2025
Allele: Dmel\IdeEP3099
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General Information
Symbol
Dmel\IdeEP3099
Species
D. melanogaster
Name
FlyBase ID
FBal0246263
Feature type
allele
Associated gene
Dmel\Ide
Associated Insertion(s)
P{EP}RhoBTBEP3099
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}RhoBTBEP3099
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  Alzheimer's disease 1
        modeled by Hsap\APPAβ42.UAS.cUa
        (Upadhyay et al., 2023)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression using Scer\GAL4ey.PU does not induce a rough eye phenotype.

        (Cao et al., 2008)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        NOT Suppressor of
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        IdeEP3099/Scer\GAL4ey.PU is an enhancer of eye phenotype of Hsap\APPAβ42.GMR.Tag:SS(rPENK)

        (Cao et al., 2008)
        Suppressor of
        Statement
        Reference

        IdeEP3099, Scer\GAL4GMR.PU is a suppressor | partially of eye phenotype of Hsap\APPAβ42.UAS.cUa, Scer\GAL4GMR.PU

        (Upadhyay et al., 2023)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        Co-expression of IdeEP3099 does not suppress the reduced life span seen in Hsap\APPAβ42.Scer\UAS, Scer\GAL4elav-C155 flies.

        (Finelli et al., 2004)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        IdeEP3099
        Name Synonyms
        Secondary FlyBase IDs
          References (3)