FB2025_01 , released February 20, 2025
Allele: Dmel\Scox2rev44.2
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General Information
Symbol
Dmel\Scox2rev44.2
Species
D. melanogaster
Name
FlyBase ID
FBal0246273
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
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Allele class
Nature of the Allele
Allele class
Associated Insertion(s)
Cytology
Description

Imprecise excision of P{lacW}ScoxSH1783, leaving 38 bp of the P{lacW} element at the insertion site, including the 8 bp P-element target site duplication and part of the 3'-5' P{lacW} terminal inverted repeat. This residual insertion generates a frameshift producing a prematurely terminated novel reading frame putatively encoding a 77 amino acid polypeptide - only the first 48 amino acids match those in the wild type nascent protein.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

38 residual bases of the Pelement along with the 8 bp repeat are inserted at the site, leading to a frameshift and early translation termination after 71 aa (48 of which are from wt Scox).

Inserted_sequence:

CATGATGAAATAACATGTTATTTCATCATGGTCTGGCC

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
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Reference
 
Marker for
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Reporter construct used in assay
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Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
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Xenogenetic Interactions
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Complementation and Rescue Data
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Mutant
Wild-type
Stocks (0)
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External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scox2rev44.2
scox2rev44.2
Name Synonyms
Secondary FlyBase IDs
    References (1)