Allele Dmel\Clk^T:SV5\V5

General Information
Symbol	Dmel\Clk^T:SV5\V5	Species	D. melanogaster
Name		FlyBase ID	FBal0246365
Feature type	allele	Associated gene	Dmel\Clk

Allele class
Mutagen	in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Kadener et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference A 14.kb genomic fragment containing the Clk gene, which has been tagged with T:SV5\V5. (Kadener et al., 2008)
Carried in construct	P{Clk.V5} (Kadener et al., 2008, Kadener et al., 2009, Abruzzi et al., 2011, Kaasik et al., 2013)
Tagged with	T:SV5\V5 (Kadener et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	locomotor rhythm defective (Kadener et al., 2008)
Phenotype Manifest In

Detailed Description
	Statement Reference Flies carrying several copies of Clk[T:SV5\V5] have a shorter circadian locomotor activity period than control flies. (Kadener et al., 2008)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	Clk^T:SV5\V5 partially rescues Clk^ar (Kadener et al., 2009)
Comments	Clk[T:SV5\V5] significantly rescues the arrhythmic locomotor behaviour of Clk[ar] flies. (Kadener et al., 2009)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Clk^T:SV5\V5
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Kaasik et al., 2013, Cell Metab. 17(2): 291--302 Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock. [FBrf0220792] Abruzzi et al., 2011, Genes Dev. 25(22): 2374--2386 Drosophila CLOCK target gene characterization: implications for circadian tissue-specific gene expression. [FBrf0216798] Kadener et al., 2009, Genes Dev. 23(18): 2179--2191 A role for microRNAs in the Drosophila circadian clock. [FBrf0209082] Kadener et al., 2008, PLoS Biol. 6(5): e119 Circadian transcription contributes to core period determination in Drosophila. [FBrf0204901]

Allele Dmel\ClkT:SV5\V5

Allele Dmel\Clk^T:SV5\V5