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General Information
Symbol
Dmel\msl-1P864L
Species
D. melanogaster
Name
FlyBase ID
FBal0246500
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
msl1P864L
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C18685775T

Reported nucleotide change:

C?T

Amino acid change:

P864L | msl-1-PA; P864L | msl-1-PB

Reported amino acid change:

P864L

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: P864L.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Males carrying P{GMroX1}75C and heterozygous for msl-1P864L have solid red eyes.

msl-1P864L/msl-1S943F transheterozygous males and females exhibit a decreased adult lifespan compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

P{GMroX1}75C (which carries roX1t4.9) is still able to partially rescue the lethality of roX1ex6/Df(1)52 males if the males are also heterozygous for msl-1P864L.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)