Open Close
General Information
Symbol
Hsap\SLC12A5UAS.cHa
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct a of Hekmat-Scafe
FlyBase ID
FBal0246599
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a 3.4 kb Hsap\SLC12A5 cDNA fragment.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
ameliorates  epilepsy
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of two copies of Hsap\SLC12A5Scer\UAS.cHa driven by two copies of Scer\GAL4c739 results in an almost complete rescue of the bang-sensitive paralytic phenotype of homozygous kccDHS1 mutants. Electrophysiology shows that Hsap\SLC12A5Scer\UAS.cHa expression raises the seizure threshold of kccDHS1 mutant flies.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Hsap\SLC12A5Scer\UAS.cHa
Hsap\SLC12A5UAS.cHa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Hekmat-Scafe
Secondary FlyBase IDs
    References (1)