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General Information
Symbol
Dmel\DaxxU26
Species
D. melanogaster
Name
FlyBase ID
FBal0246798
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:
Approximate boundaries of 1.7 kb deletion resulting from the imprecise excision of P{RS3}DLPCB-6241-3 (curator deduction from description - one of two insertions in the first intron of DLP used for creating excisions). The deletion takes out part of the intron and 1296 bp of exon 2.
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Imprecise excision of an insertion in the first intron of DLP, resulting in a 1.7kb deletion that removes the downstream part of the first intron and 1296bp of coding sequence from the second exon.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Mutant third instar larvae show no reduction in survival after irradiation with 2krad X rays compared to control larvae. Homozygotes show a decreased rate of loss of heterozygosity (LOH) after irradiation compared to control flies. The average number of eggs laid by DaxxU32/DaxxU26 females in a 24 hour interval is significantly less than the number laid by control females. The median of the lifespan of homozygous males is significantly decreased compared to that of control males. Mutant third instar larvae show no reduction in survival after irradiation with 2krad X rays compared to control larvae. The average number of eggs laid by DaxxU32/DaxxU26 females in a 24 hour interval is significantly less than the number laid by control females. The median of the lifespan of homozygous males is significantly decreased compared to that of control males.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Two-thirds of animals expressing p53Scer\UAS.cJa under the control of Scer\GAL4Act5C.PI in a DLPU26/DLPU26 background die in early pupal stage and only 9% of them eclose.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
DaxxU26
Name Synonyms
Secondary FlyBase IDs
    References (1)