|Feature type||allele||Associated gene||Dmel\kis|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Phenotype Manifest In|
Homozygous γ Kenyon neurons undergo proper dendritic pruning during pupal development, but they display defects in their axonal pruning and continue to display unpruned γ axons projecting into the α lobes 40% of the time in pupal brains. Cells in homozygous clones in the α, β and γ lobes of the mushroom body have normal dendrite morphology, but show axonal migration defects with axons crossing the midline (55% penetrance), cell position defects (36% penetrance) and defects in the morphology of the lobe (55% penetrance). Homozygous dorsal cluster neuron clones in the larva show a number of defects; 53% show abnormalities in position within the brain, 32% show defects in axon migration (the neurons fail to migrate to their proper contralateral targets) and 32% of cell bodies are not part of the larger cell body cluster. Homozygous adult dorsal cluster neurons do not show defects in dendrite formation. However, they show a severe reduction in the number of axons extending into the lobula and subsequently extending from the lobula into the medulla. Homozygous clones in the developing third instar larval retina show abnormal axonal migration into the developing brain, with photoreceptor axons extending beyond their normal targets and radiating out into the surrounding brain areas. These axons also show abnormal defasciculation of axonal bundles in the optic stalk. External eye morphology appears normal in adults containing homozygous clones in the retina.
|Phenotype Manifest In|
|Complementation & Rescue Data|
|Fails to complement|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 2 )|
|Secondary FlyBase IDs|
|References ( 2 )|