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General Information
Symbol
Dmel\β-SpecM.UAS.Tag:MYC
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct A of Mazock
FlyBase ID
FBal0246997
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of β-Spec coding sequences tagged with a Tag:MYC epitope.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
β-Specem6 mutants expressing β-SpecM.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155 are short lived compared to controls.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Nervous system expression of β-SpecM.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155 is sufficient to allow a high rate of survival of β-Specem6 males. Reared at 25[o]C, male progeny appear somewhat unhealthy with crumpled wings, rough eyes, small size and are short-lived. Nevertheless, these males are fertile and thus represent a significant rescue of embryonic lethality. At a reduced temperature (22[o]C), the level of β-SpecScer\UAS.T:Hsap\MYC expression is reduced and the appearance of the rescued flies is closer to wild-type (i.e. wings are properly unfolded and the thorax and abdomen are full-size).
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
β-SpecM.Scer\UAS.T:Hsap\MYC
β-SpecM.UAS.Tag:MYC
Name Synonyms
Saccharomyces cerevisiae UAS construct A of Mazock
Secondary FlyBase IDs
    References (1)