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General Information
Symbol
Dmel\bazS980A.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0247042
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of baz carrying a S980A substitution, tagged at the N-terminus with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos expressing bazS980A.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4da.G32 display severely disrupted epithelial morphogenesis and degeneration of the epidermis. Mutant embryos are open dorsally, and internal organs including the foregut and midgut protrude to the outside. Many epidermal cells round up and die by apoptosis.

Expression of bazS980A.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4arm.PS results in only little scraps of cuticle formation.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of crbintra.Scer\UAS and bazS980A.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4da.G32 results in the same phenotype as overexpression of bazS980A.Scer\UAS.T:Avic\GFP alone. Only little scraps of embryonic cuticle are observed.

The cuticle defects observed when bazS980A.Scer\UAS.T:Avic\GFP is expressed under the control of Scer\GAL4arm.PS are strongly suppressed in a l(2)gl4 or scrib673 mutant background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
bazS980A.Scer\UAS.T:Avic\GFP
bazS980A.UAS.GFP
Name Synonyms
Secondary FlyBase IDs
    References (1)