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General Information
Symbol
Dmel\His2AvmRFP1
Species
D. melanogaster
Name
FlyBase ID
FBal0247236
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
His2Av-mRFP1, His2Av-mRFP, histone-RFP, His2Av-RFP, H2Av-mRFP, H2Av-mRFP1, His2AvD-mRFP, H2AvD-mRFP, H2A-RFP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Composed of three distinct fragments. First, a 2240 bp His2Av PCR fragment encompassing 751 bp upstream of the His2Av translational initiation codon and the complete His2Av coding region up to the ultimate codon. This is fused to a second PCR fragment encompassing the mRFP1 coding region. A third PCR fragment encompassing 1690 bp of genomic His2Av 3' flanking DNA is cloned downstream of the His2Av-mRFP1 fusion protein.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of His2AvT:Disc\RFP-mRFP rescues the spermatocyte loss seen in His2Av810 testes containing germline stem cell clones. The loss of His2Av810 mutant cyst stem cells (CySCs) is also rescued.

Images (0)
Mutant
Wild-type
Stocks (9)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
His2AvP.T:Disc\RFP-mRFP
His2AvT:Disc\RFP-mRFP
His2AvmRFP1
Name Synonyms
Secondary FlyBase IDs
  • FBal0243442
  • FBal0189789
References (59)