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General Information
Symbol
Dmel\Ilp8MI00727
Species
D. melanogaster
Name
FlyBase ID
FBal0247717
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dilp8MI00727
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Ilp8 mRNA expression is reduced by 99.4%.

    Insertion components
    Mi{MIC}Ilp8MI00727
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    distribution deduced from reporter or direct label
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous flies show a significant increase in fluctuating asymmetry of left and right wing areas compared to controls.

    Ilp8MI00727 shortens the delay in pupariation induced by EMS by 44.03%.

    Ilp8MI00727 animals pupate over an extended timescale and are more varied in size compared to controls sharing the same genetic background. Individually, Ilp8MI00727 flies reared at 26.5[o]C display imperfect bilateral symmetry, as assayed by right vs left wing size.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    NOT Enhancer of
    Statement
    Reference
    Suppressor of
    NOT Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    NOT Enhancer of
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference

    Ilp8[+]/Ilp8MI00727 is a non-suppressor of wing | ectopic phenotype of CtBP87De-10, Scer\GAL4rn-GAL4-5, egrUAS.cUa

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Co-expression of DlScer\UAS.cDa, lolaGS88A8 and psqGS88A8 using Scer\GAL4ey.PH (the so-called 'eyeful' background) results in a delay in pupariation of 26.6 +/- 7.5 hours. This is reverted to a delay of 5.9 +/- 7.1 hours in a Ilp8MI00727 background.

    The 46.2 +/- 1.3 hours delay in pupariation in rprScer\UAS.C, Scer\GAL4Bx-MS1096 animals is reverted to a delay of 27.8 +/- 2.9 hours in a Ilp8MI00727 background.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    CG14059MI00727
    Ilp8MI00727
    dIlp8MI00727
    dilp8MI00727
    Name Synonyms
    Secondary FlyBase IDs
      References (5)