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General Information
Symbol
Dmel\DaxxEY09290
Species
D. melanogaster
Name
FlyBase ID
FBal0248772
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EY09290
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EPgy2}DaxxEY09290
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Flies expressing DLPEY09290 under the control of Scer\GAL4elav.PU are more sensitive to treatment with hydrogen peroxide than controls. Expression of DLPEY09290 under the control of Scer\GAL4Bx-MS1096 results in a reduction in wing size, in a dose-sensitive manner. High levels of apoptosis are seen in the wing discs in these animals.
Expression of DLPEY09290 driven by Scer\GAL4Act5C.PI results in lethality.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Suppressor of
Statement
Reference
Phenotype Manifest In
Enhanced by
Suppressed by
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of thScer\UAS.cHa almost completely suppresses the reduction in wing size caused by expression of DLPEY09290 under the control of Scer\GAL4Bx-MS1096. The reduced wing phenotype caused by expression of DLPEY09290 under the control of Scer\GAL4Bx-MS1096 is strongly exacerbated by co-expression of either bskScer\UAS.cBa or hepScer\UAS.cBa and is suppressed by co-expression of pucScer\UAS.cMa. The reduced wing phenotype caused by expression of DLPEY09290 under the control of Scer\GAL4Bx-MS1096 is suppressed by bsk1, by foxo21 and by hep1.
Mis-expression of DLPEY09290 driven by Scer\GAL4GMR.PF results in increased eye pigmentation in bwD/+ heterozygotes compared with that in the parental bwD/+ line.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
DLPEY09290
DaxxEY09290
Name Synonyms
Secondary FlyBase IDs
    References (2)