FlyBase Allele Report: Dmel\rdx[Δ6]

General Information

Symbol

Dmel\rdx^Δ6

Species

D. melanogaster

Name

FlyBase ID

FBal0249008

Feature type

allele

Associated gene

Dmel\rdx

Associated Insertion(s)

TI{TI}rdx^Δ6

Carried in Construct

Also Known As

hib^Δ6

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

recombination

(Zhang et al., 2006)

FLPase

(Zhang et al., 2006)

I-SceI

(Zhang et al., 2006)

ends-out gene targeting

(Zhang et al., 2006)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

The rdx coding sequence has been replaced by a w^+* marker.

(Zhang et al., 2006)

Insertion components

TI{TI}rdx^Δ6

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | somatic clone

(Zhang et al., 2006)

Phenotype Manifest In

eye

(Zhang et al., 2006)

Detailed Description

Statement

Reference

Homozygous clones in the eye result in a mild rough eye phenotype.

(Zhang et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scer\GAL4^GMR.PF, ci^{-3P.UAS.W.Tag:HA}, rdx^Δ6 has visible | somatic clone phenotype

(Zhang et al., 2006)

Scer\GAL4^GMR.PF, ci^UAS.W.Tag:HA, rdx^Δ6 has visible | somatic clone phenotype

(Zhang et al., 2006)

Scer\GAL4^GMR.PF, Xlae\Gli2^UAS.Tag:MYC, rdx^Δ6 has visible | somatic clone phenotype

(Zhang et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

rdx^Δ6 is an enhancer of wing disc phenotype of Scer\GAL4^Bx-MS1096, ci^{-3P.UAS.W.Tag:HA}

(Zhang et al., 2006)

Other

Statement

Reference

Scer\GAL4^GMR.PF, ci^{-3P.UAS.W.Tag:HA}, rdx^Δ6 has eye | somatic clone phenotype

(Zhang et al., 2006)

Scer\GAL4^GMR.PF, ci^UAS.W.Tag:HA, rdx^Δ6 has eye | somatic clone phenotype

(Zhang et al., 2006)

Scer\GAL4^GMR.PF, Xlae\Gli2^UAS.Tag:MYC, rdx^Δ6 has eye | somatic clone phenotype

(Zhang et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The wing disc overgrowth phenotype caused by expression of ci^{-3P.Scer\UAS.W.T:Ivir\HA1} under the control of Scer\GAL4^Bx-MS1096 is greatly enhanced by rdx^Δ6, with the double mutant cells forming tumour-like overgrowths.

Expression of either ci^{-3P.Scer\UAS.W.T:Ivir\HA1} or ci^{Scer\UAS.W.T:Ivir\HA1} under the control of Scer\GAL4^GMR.PF in eyes carrying homozygous rdx^Δ6 clones results in a severe rough eye phenotype.

(Zhang et al., 2006)

Xenogenetic Interactions

Statement

Reference

Expression of Xlae\Gli2^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF in eyes carrying homozygous rdx^Δ6 clones results in a severe rough eye phenotype.

(Zhang et al., 2006)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

hib^Δ6

(Zhou et al., 2015, Zhang et al., 2009, Zhang et al., 2006)

hib^Δ

(Liu et al., 2014)

rdx^Δ6

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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