FB2025_05 , released December 11, 2025
Allele: Scer\GAL4GMR46F09
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General Information
Symbol
Scer\GAL4GMR46F09
Species
S. cerevisiae
Name
FlyBase ID
FBal0252775
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR46F09-GAL4}
Also Known As
R46F09
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR46F09-GAL4}
Cytology
Description

A 4407 base pair fragment from the flanking non-coding or intronic region of hth is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR46F09
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      larval mushroom body octopaminergic/tyraminergic neuron e1
      (Saumweber et al., 2018)
      adult stage | male
      ventrolateral protocerebrum projection neuron 1
      (Zhou et al., 2015)
      adult stage | female
      ventrolateral protocerebrum projection neuron 1
      (Zhou et al., 2015)
      Additional Information
      Statement
      Reference

      A FLP/FRT intersectional strategy shows expression of ScerGAL4GMR46F09 in ventrolateral protocerebrum projection neuron 1 when combined with EcollexAfru.P1.

      (Zhou et al., 2015)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\TeTxLCFRT.stop.UAS with Scer\FLP1L.8xlexAop) of neurons expressing Ecol\lexAfru.P1 and Scer\GAL4GMR46F09 significantly reduces male-male courtship chaining responses to pulse song, compared to controls.

      Optogenetic activation (using Cnoc\ChR1Cs.20xUAS.FRT.Venus with Scer\FLP1L.8xlexAop and activating with 655 nm (red) light) of neurons expressing Ecol\lexAfru.P1 and Scer\GAL4GMR46F09 significantly increases male-male courtship chaining, compared to controls.

      (Zhou et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR46F09
      Name Synonyms
      Secondary FlyBase IDs
        References (4)