FB2022_03, released June 9, 2022

Allele: Scer\GAL4GMR71G01

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General Information
Symbol
Scer\GAL4GMR71G01
Species
S. cerevisiae
Name
FlyBase ID
FBal0254464
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR71G01-GAL4}
Also Known As
R71G01-Gal4, R71G01, 71G01-Gal4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Pfeiffer et al., 2011.2.9)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{GMR71G01-GAL4}
      Cytology
      Nature of the lesion
      Statement
      Reference

      A 3844 base pair fragment from the flanking non-coding or intronic region of Vsx2 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

      (Pfeiffer et al., 2011.2.9)
      Allele components
      Product class / Tool use(s)
      Encoded product / tool
      GAL4
      Associated Sequence Features
      GMR71G01
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      neuron | subset of adult brain
      (Pan et al., 2012)
      neuron | subset of adult ventral nerve cord
      (Pan et al., 2012)
      adult fruitless pMP-e (female) neuron | subset
      (Pan et al., 2012)
      superior clamp | faint | restricted
      (Jenett and Svirskas, 2012.9.24)
      fruitless expressing neuron | subset
      (Clowney et al., 2015)
      adult fruitless P1 (male) neuron
      (Jung et al., 2020)
      adult stage | male
      adult doublesex pC1 (male) neuron | subset
      (Zhou et al., 2014)
      adult brain | restricted
      (Hoopfer et al., 2015)
      adult fruitless P1 (male) neuron | subset
      (Hoopfer et al., 2015)
      adult ventral nerve cord | restricted
      (Hoopfer et al., 2015)
      adult stage | female
      adult brain | restricted
      (Hoopfer et al., 2015)
      adult ventral nerve cord | restricted
      (Hoopfer et al., 2015)
      Additional Information
      Statement
      Reference

      Scer\GAL4GMR71G01 is expressed in 19-23 fru positive adult fruitless pMP-e (male) neurons and 100-150 other neurons in the male brain.

      (Hoopfer et al., 2015)

      Scer\GAL4GMR71G01 drives expression in a subset of adult doublesex pC3 (male) neurons that also express Ecol\lexAfru.P1.

      (Zhou et al., 2014)

      Scer\GAL4GMR71G01 drives expression in a subset of neurons in the adult CNS, including the male specific P1 (pMP-e) neurons in the brain.

      (Pan et al., 2012)
       
      Marker for
      Reflects expression of
      dsx
      (Zhou et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 31[o]C) of Scer\GAL4GMR71G01 cells, or the combined set of Scer\GAL4GMR71G01 and Scer\GAL4NPF.1 cells, in adult males does not affect courtship towards females or males, compared to controls.

      (Liu et al., 2019)

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 29[o]C) of Scer\GAL4GMR71G01 cells in adult males significantly increases aggressive lunging behavior and wing extensions towards other males, compared to controls.

      Thermogenetic activation (using TrpA1FRT.stop.UAS.Tag:MYC at 29[o]C) of a Scer\FLP1fru-expressing subset of Scer\GAL4GMR71G01 cells in adult males significantly increases aggressive lunging behavior, but not wing extensions, towards other males, compared to controls.

      (Hoopfer et al., 2015)

      Inhibition of neural activity in Scer\GAL4GMR71G01-expressing neurons results in courtship defects.

      (Shankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR71G01
      Name Synonyms
      Secondary FlyBase IDs
        References (18)