FB2025_01 , released February 20, 2025
Allele: Scer\GAL4GMR61D08
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General Information
Symbol
Scer\GAL4GMR61D08
Species
S. cerevisiae
Name
FlyBase ID
FBal0256493
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR61D08-GAL4}
Also Known As
R61D08-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR61D08-GAL4}
Cytology
Description

A 741 base pair fragment from the robl region, including the putative endogenous robl promoter, is fused upstream of sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR61D08
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      chordotonal neuron
      (Jovanic et al., 2016)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\TeTxLC[TNT.UAS]) of Scer\GAL4GMR61D08 neurons in larvae significantly reduces navigation away from higher wind speeds, compared to controls, with no effect on movement speed in the absence of wind stimuli; there is no effect on the probability of head turns downwind or acceptance rates of head sweeps away from versus towards the wind, compared to controls.

      Inhibition (using Ctet\TeTxLC[TNT.UAS]) of the combined set of Scer\GAL4GMR61D08 and Scer\GAL419-12 neurons in larvae significantly reduces navigation away from higher wind speeds, compared to controls; this effect is slightly greater than that of inhibiting Scer\GAL4GMR61D08 neurons alone; there is also a significant reduction in the probability of head turns downwind and acceptance rates of head sweeps away from versus towards the wind, compared to controls and compared to Scer\GAL419-12 neurons alone.

      (Jovanic et al., 2019)

      Inhibition (using shits.FRT.stop.UAS at 30[o]C) of Scer\GAL4GMR61D08 neurons that also express Scer\FLP1ey.PU in adult females significantly reduces receptivity to mating, compared to controls; in males, courtship pulse song-induced locomotion is significantly reduced, compared to controls.

      (Vaughan et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR61D08
      Name Synonyms
      Secondary FlyBase IDs
        References (6)