FB2025_01 , released February 20, 2025
Allele: Dmel\ltl1
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General Information
Symbol
Dmel\ltl1
Species
D. melanogaster
Name
FlyBase ID
FBal0256896
Feature type
allele
Associated gene
Dmel\ltl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Szuperák et al., 2011)
Progenitor genotype
Cytology
Description

FlyBase curator comment: amino acid replacement Q15term (rather than G15term reported in paper) inferred from sequence and very small likelihood of reported amino acid change occurring.

(Szuperák et al., 2011)

Amino acid replacement: Q15term.

(Szuperák et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:7,519,727..7,519,727 [+]
Nucleotide change:

C7519727T

Amino acid change:

Q15term | ltl-PA; Q15term | ltl-PB

Reported amino acid change:

G15term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. The reported location of G15term appears to be a typo for Q15term.

(Szuperák et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ltl1/ltl4 animals survive to adulthood and have wing defects including subtle modifications of wing size and shape, along with ectopic vein material associated with wing vein L2 and the anterior and posterior crossveins.

      (Szuperák et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ltl1
      (Szuperák et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)