FB2025_01 , released February 20, 2025
Allele: Dmel\ltlUAS.Tag:HA,Tag:FLAG
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General Information
Symbol
Dmel\ltlUAS.Tag:HA,Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0256904
Feature type
allele
Associated gene
Dmel\ltl
Associated Insertion(s)
Carried in Construct
P{UAS-ltl.HA-2XFLAG}
Key Links
Transgenic product class
wild_type
(Szuperák et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Szuperák et al., 2011)
Mutagen
in vitro construct
(Szuperák et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-ltl.HA-2XFLAG}
Cytology
Description

UAS regulatory sequences drive expression of ltl which is tagged at the C-terminal end with Tag:HA and with Tag:FLAG.

(Szuperák et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ltl
Tagged with
Tag:FLAG
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ltlScer\UAS.T:Ivir\HA1,T:Zzzz\FLAG under the control of Scer\GAL4A9 results in an approximately 14% reduction in wing size.

      (Szuperák et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dlpScer\UAS.T:Ivir\HA1 and ltlScer\UAS.T:Ivir\HA1,T:Zzzz\FLAG under the control of Scer\GAL4A9 disrupts wing morphogenesis and results in an approximately 42% reduction in wing size.

      (Szuperák et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ltlScer\UAS.T:Ivir\HA1,T:Zzzz\FLAG
      ltlUAS.Tag:HA,Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)