Allele Scer\GAL4^Mhc.PU

General Information
Symbol	Scer\GAL4^Mhc.PU	Species	S. cerevisiae
Name	Myosin heavy chain promoter construct of Unknown	FlyBase ID	FBal0256907
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02	Controlled Vocabulary Terms viable
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Kasuya et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Mhc promoter sequences drive expression of Scer\GAL4. (Kasuya et al., 2009)
Carried in construct	P{Mhc-GAL4.U} (Lin et al., 2011, Guan et al., 2011, Kasuya et al., 2009, Bahadorani et al., 2010, Saraswati et al., 2007, Bhogal et al., 2011, Tsai et al., 2012, Dickman et al., 2012, Pascual et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage, with Lapsyn^Scer\UAS.cGa, Lapsyn^zg1 (Guan et al., 2011) neuroanatomy defective \| third instar larval stage, with fz2^Scer\UAS.N (Tsai et al., 2012) viable, with LamC^{G489V.Scer\UAS} (Dialynas et al., 2012) viable, with LamC^{M553R.Scer\UAS} (Dialynas et al., 2012) viable, with LamC^{N496I.Scer\UAS} (Dialynas et al., 2012) viable, with LamC^Scer\UAS.cSa (Dialynas et al., 2012) viable, with LamC^{V528P.Scer\UAS} (Dialynas et al., 2012)
Phenotype Manifest In
	neuromuscular junction \| third instar larval stage, with fz2^Scer\UAS.N (Tsai et al., 2012)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Scer\GAL4^Mhc.PU, fz2^Scer\UAS.N has neuroanatomy defective \| third instar larval stage phenotype, suppressible by Itgβν¹/betaInt-nu[+] (Tsai et al., 2012) Scer\GAL4^Mhc.PU, fz2^Scer\UAS.N has neuroanatomy defective \| third instar larval stage phenotype, suppressible by LanA^9-32/LanA[+] (Tsai et al., 2012)
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^Mhc.PU, fz2^Scer\UAS.N has neuromuscular junction \| third instar larval stage phenotype, suppressible by Itgβν¹/betaInt-nu[+] (Tsai et al., 2012) Scer\GAL4^Mhc.PU, fz2^Scer\UAS.N has neuromuscular junction \| third instar larval stage phenotype, suppressible by LanA^9-32/LanA[+] (Tsai et al., 2012)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	Lapsyn^Scer\UAS.cGa/Scer\GAL4^Mhc.PU fails to rescue Lapsyn^zg1 (Guan et al., 2011) Scer\GAL4^Mhc.PU/Adar^3.4.Scer\UAS fails to rescue Adar^5G1 (Bhogal et al., 2011)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Scer\GAL4^Mhc.PU
Name Synonym	Myosin heavy chain promoter construct of Unknown
Secondary FlyBase IDs

References ( 10 )
Research paper	Dialynas et al., 2012, Hum. Mol. Genet. 21(7): 1544--1556 LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle. [FBrf0217713] Dickman et al., 2012, J. Neurosci. 32(25): 8716--8724 Snapin is Critical for Presynaptic Homeostatic Plasticity. [FBrf0218676] Tsai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(43): 17699--17704 Activity-dependent retrograde laminin A signaling regulates synapse growth at Drosophila neuromuscular junctions. [FBrf0219768] Bhogal et al., 2011, Nat. Neurosci. 14(12): 1517--1524 Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. [FBrf0216747] Guan et al., 2011, Learn. Mem. 18(4): 191--206 Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. [FBrf0213277] Lin et al., 2011, PLoS ONE 6(6): e20371 Neuronal Function and Dysfunction of Drosophila dTDP. [FBrf0213971] Bahadorani et al., 2010, Aging Cell 9(2): 191--202 Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan. [FBrf0210626] Pascual et al., 2010, Fly 4(4): 333--337 A GFP-tagged Muscleblind C protein isoform reporter construct. [FBrf0212519] Kasuya et al., 2009, Neuroscience 163(3): 825--837 A putative amino acid transporter of the solute carrier 6 family is upregulated by lithium and is required for resistance to lithium toxicity in Drosophila. [FBrf0209152] Saraswati et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104(35): 14122--14127 Characterization of the role of the Synaptotagmin family as calcium sensors in facilitation and asynchronous neurotransmitter release. [FBrf0201175]

Allele Scer\GAL4Mhc.PU

Allele Scer\GAL4^Mhc.PU