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General Information
Symbol
Dmel\kstβH33.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0256987
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a C-terminal fragment of kst.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of kstβH33.Scer\UAS under the control of Scer\GAL4GMR.PFa produces a strong rough-eye phenotype with dorsal posterior roughness, loss of pigmentation and often some necrosis.

Sustained expression of kstβH33.Scer\UAS throughout eye development using the Scer\GAL4ey.200.Exel driver results in significant reduction in eye size and the occasional replacement of eye tissue with cuticle with bristle.

Expression of kstβH33.Scer\UAS under the control of Scer\GAL4AB1 does not increase the diameter of the salivary gland lumen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of kstβH33.Scer\UAS and trioScer\UAS.cBa under the control of Scer\GAL4GMR.PFa suppresses the roughness of both the kstβH33.Scer\UAS and the trioScer\UAS.cBa eye phenotype.

Co-expression of tumdsRNA.Scer\UAS.cBa with kstβH33.Scer\UAS under the control of Scer\GAL4GMR.PFa suppresses the eye phenotype resulting from the expression of kstβH33.Scer\UAS alone.

Co-expression of trioScer\UAS.cBa with kstβH33.Scer\UAS under the control of Scer\GAL4ey.200.Exel suppresses the eye phenotype resulting from the overexpression of kstβH33.Scer\UAS.

Expression of kstβH33.Scer\UAS in combination with PakScer\UAS.T:Myr1 under the control of Scer\GAL4AB1 strongly suppresses the salivary gland lumen size defect caused by PakScer\UAS.T:Myr1 expression.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
kstβH33.Scer\UAS
kstβH33.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)