|Feature type||allele||Associated gene||Dmel\bft|
|Mutagen||recombination, ends-out gene targeting|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Phenotype Manifest In|
Homozygous and bft[Δ263a]/bft flies show loss of approximately 80% of interommatidial bristles. bft[Δ263a]/bft[Δ263a-G4] flies show loss of interommatidial bristles. The mutant retina appears normal in homozygous flies at 24 hours after puparium formation (APF). However, the majority of bristle shaft progenitor cells are missing in the mutant retina at 40 hours APF. Apoptotic nuclei corresponding to the bristle shaft cells are seen in the mutant retina at 35 hours APF.
bft24/bftΔ263a has visible phenotype, suppressible by Scer\GAL4mir-263b-Δ-G4/mir-263bScer\UAS.T:Disc\RFP-DsRed2
|Phenotype Manifest In|
bft24/bftΔ263a has interommatidial bristle phenotype, suppressible by Scer\GAL4mir-263b-Δ-G4/mir-263bScer\UAS.T:Disc\RFP-DsRed2
bftunspecified/bftΔ263a has interommatidial bristle phenotype, suppressible | partially by W05014/W[+]
The loss of interommatidial bristles seen in bft[Δ263a]/bft flies is significantly enhanced if the flies are also carrying mir-263b[Δ]/Df(3L)X-21.2. Expression of mir-263b[Scer\UAS.T:Disc\RFP-DsRed2] under the control of Scer\GAL4[mir-263b-Δ-G4] rescues the loss of interommatidial bristles which is seen in bft[Δ263a]/bft flies. W/+ and W/+ each partially suppress the loss of interommatidial bristles which is seen in bft[Δ263a]/bft[unspecified] flies. Expression of W[GD1673] under the control of Scer\GAL4[mir-263b-Δ-G4] strongly suppresses the loss of interommatidial bristles which is seen in bft[Δ263a]/bft[unspecified] flies.
|Complementation & Rescue Data|
|Partially rescued by|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 2 )|
|Secondary FlyBase IDs|
|References ( 1 )|