Allele Dmel\bft^Δ263a-G4

General Information
Symbol	Dmel\bft^Δ263a-G4	Species	D. melanogaster
Name		FlyBase ID	FBal0257040
Feature type	allele	Associated gene	Dmel\bft

Allele class
Mutagen	recombination, gene targeting by homologous recombination
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	gene targeting by homologous recombination (Hilgers et al., 2010) recombination (Hilgers et al., 2010)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Homologous recombination at the bft locus has been used to replace the mir-263a miRNA hairpin (which is encoded by bft) with the Scer\GAL4 coding region and a mini-w marker. (Hilgers et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	visible (with bft²⁴) (Hilgers et al., 2010) visible (with bft^Δ263a) (Hilgers et al., 2010)
Phenotype Manifest In
	interommatidial bristle (with bft²⁴) (Hilgers et al., 2010) interommatidial bristle (with bft^Δ263a) (Hilgers et al., 2010)
Detailed Description
	Statement Reference bft[Δ263a-G4]/bft[24] and bft[Δ263a]/bft[Δ263a-G4] flies show loss of interommatidial bristles. (Hilgers et al., 2010)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference bft^unspecified/bft^Δ263a-G4 has visible phenotype, suppressible by Scer\GAL4^{bft-Δ263a-G4}/BacA\p35^Scer\UAS.cHa (Hilgers et al., 2010) bft^unspecified/bft^Δ263a-G4 has visible phenotype, suppressible by Scer\GAL4^{bft-Δ263a-G4}/th^Scer\UAS.cHa (Hilgers et al., 2010)
Phenotype Manifest In
Suppressed by
Statement Reference bft^unspecified/bft^Δ263a-G4 has interommatidial bristle phenotype, suppressible by Scer\GAL4^{bft-Δ263a-G4}/BacA\p35^Scer\UAS.cHa (Hilgers et al., 2010) bft^unspecified/bft^Δ263a-G4 has interommatidial bristle phenotype, suppressible by Scer\GAL4^{bft-Δ263a-G4}/th^Scer\UAS.cHa (Hilgers et al., 2010)
Additional Comments
Genetic Interactions
Statement Reference Expression of th[Scer\UAS.cHa] under the control of Scer\GAL4[bft-Δ263a-G4] suppresses the loss of interommatidial bristles which is seen in bft[Δ263a-G4]/bft[unspecified] flies. (Hilgers et al., 2010)
Xenogenetic Interactions
Statement Reference Expression of BacA\p35[Scer\UAS.cHa] under the control of Scer\GAL4[bft-Δ263a-G4] suppresses the loss of interommatidial bristles which is seen in bft[Δ263a-G4]/bft[unspecified] flies. (Hilgers et al., 2010)
Complementation & Rescue Data
Rescued by	bft²⁴/bft^Δ263a-G4 is rescued by Scer\GAL4^{bft-Δ263a-G4}/bft^{Scer\UAS.T:Disc\RFP-DsRed2} (Hilgers et al., 2010)
Comments	Expression of bft[Scer\UAS.T:Disc\RFP-DsRed2] under the control of Scer\GAL4[bft-Δ263a-G4] rescues the loss of interommatidial bristles which is seen in bft[Δ263a-G4]/bft[24] flies. (Hilgers et al., 2010)
Stocks ( 0 )

Notes on Origin
Discoverer
	Associated with: Scer\GAL4[bft-Δ263a-G4]. (Hilgers et al., 2010)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	bft^Δ263a-G4 Δ263a-G4 (Hilgers et al., 2010)
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Hilgers et al., 2010, PLoS Biol. 8(6): e1000396 Drosophila microRNAs 263a/b Confer Robustness during Development by Protecting Nascent Sense Organs from Apoptosis. [FBrf0211074]

Allele Dmel\bftΔ263a-G4

Allele Dmel\bft^Δ263a-G4