Expression of Pten^HMS00044 under the control of Scer\GAL4^en-e16E leads to increased cell death and an increase in the size of posterior compartment of third instar wing discs.

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in a large eye phenotype.

Posterior dorsocentral bristle neurons expressing Pten^HMS00044 under the control of Scer\GAL4^pnr-MD237 show a significantly increased terminal arbor territory and significantly more synapses (Syt1 puncta) on the contralateral collateral branch, as compared to controls.

Females heterozygous for Pten^HMS00044 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to Pten^HMS00044 males results in: 77% hatching; non-maternal effect.

Pten^HMS00044, Scer\GAL4^en-e16E has increased cell death | third instar larval stage phenotype, suppressible by Pi3K92E^HMC05152, Scer\GAL4^en-e16E

Pten^HMS00044, Scer\GAL4^en-e16E has increased size | third instar larval stage phenotype, suppressible by Pi3K92E^HMC05152, Scer\GAL4^en-e16E

Pten^HMS00044, Scer\GAL4^pnr-MD237 has abnormal neuroanatomy | adult stage phenotype, suppressible by PRL-1[+]/PRL-1²

Pten^HMS00044, Scer\GAL4^pnr-MD237 has abnormal size | adult stage phenotype, suppressible by PRL-1[+]/PRL-1²

Pten^HMS00044, Scer\GAL4^en-e16E has wing disc | third instar larval stage phenotype, suppressible by Pi3K92E^HMC05152, Scer\GAL4^en-e16E

Pten^HMS00044, Scer\GAL4^en-e16E has wing disc posterior compartment | third instar larval stage phenotype, suppressible by Pi3K92E^HMC05152, Scer\GAL4^en-e16E

Pten^HMS00044, Scer\GAL4^pnr-MD237 has mechanosensory neuron of posterior dorsocentral bristle phenotype, suppressible by PRL-1[+]/PRL-1²

Pten^HMS00044, Scer\GAL4^pnr-MD237 has neuron projection | adult stage phenotype, suppressible by PRL-1[+]/PRL-1²

Pten^HMS00044, Scer\GAL4^pnr-MD237 has synapse | adult stage phenotype, suppressible by PRL-1[+]/PRL-1²