FB2025_01 , released February 20, 2025
Allele: Dmel\NoxHMS00691
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General Information
Symbol
Dmel\NoxHMS00691
Species
D. melanogaster
Name
FlyBase ID
FBal0257374
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The size distribution of regenerated adult wings in flies expressing NoxHMS00691 under the control of Scer\GAL4rn-GAL4-5 that were subjected to ablation of imaginal wing disc tissue during the larval stage, is significantly shifted towards bigger wing size compared to similarly treated controls. The regeneration appears to proceed at pace comparable to that observed in the wild-type controls (as judged by gradual increase in size of the regenerating wing pouch and rate of proliferation), also the delay in entry into pupariation is similar between the knock-down and the control regenerating larvae. Without any tissue damage the timing of pupariation in NoxHMS00691-expressing animals is not significantly different from the wild-type.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
NoxHMS00691
Name Synonyms
Secondary FlyBase IDs
    References (7)