Knockdown of mop^HMS00706 driven in the class IV dendritic arborizing sensory neuron ddaC by Scer\GAL4^ppk.1.9 leads to disruptions in pruning at 18hr (but not 0hr) after puparium formation, with dendrites still attached to the cell body (resulting from a lack of branch severing and clearance defects). Knockdown of mop^HMS00706 driven in the class IV dendritic arborizing sensory neuron ddaC by Scer\GAL4^ppk.1.9 leads to accumulation of ubiquitinated proteins (defects in multivesicular body formation) in third instar larvae. Knockdown of mop^HMS00706 driven in class I da sensory neurons by Scer\GAL4^smid-C161 or in mushroom body gamma neurons by Scer\GAL4^Tab2-201Y leads to significant disruption in dendrite or axon (respectively) severing at 24hr after puparium formation, compared to controls.

Females heterozygous for mop^HMS00706 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to mop^HMS00706 males results in: 11% hatching; egg/embryonic phenotype: "empty, all white"; maternal effect.