FlyBase Allele Report: Dmel\Kdm3[HMS00775]

General Information

Symbol

Dmel\Kdm3^HMS00775

Species

D. melanogaster

Name

FlyBase ID

FBal0257456

Feature type

allele

Associated gene

Dmel\Kdm3

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00775}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00775}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00775

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of alcohol use disorder

CEA

(Pinzón et al., 2017)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | adult stage, with Scer\GAL4^en.PU

(Dietz et al., 2015)

Phenotype Manifest In

posterior crossvein, with Scer\GAL4^en.PU

(Dietz et al., 2015)

Detailed Description

Statement

Reference

Expression of JHDM2^HMS00775 under the control of Scer\GAL4^en.PU very occasionally leads to ectopic vein formation at the posterior crossvein. Expression under the control of any of the following: Scer\GAL4^ey.PH, Scer\GAL4^GMR.PF or Scer\GAL4^nub.PK has no overt adult phenotype. Scer\GAL4^Act5C.PI-driven expression is viable.

(Dietz et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Kdm3^HMS00775, Scer\GAL4^en.PU, htt^GD14943 has visible | adult stage phenotype

(Dietz et al., 2015)

Phenotype Manifest In