FlyBase Allele Report: Dmel\CycT[HMS00776]

General Information

Symbol

Dmel\CycT^HMS00776

Species

D. melanogaster

Name

FlyBase ID

FBal0257457

Feature type

allele

Associated gene

Dmel\CycT

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00776}

Also Known As

UAS-CycT-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00776}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00776

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryo | gastrula stage | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

(Dahlberg et al., 2015)

mesoderm | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

(Dahlberg et al., 2015)

Detailed Description

Statement

Reference

Embryos from mothers expressing CycT^HMS00776 under the control of Scer\GAL4^{VP16.mat.αTub67C} show s posterior-specific loss of cells in embryos prior to gastrulation; the mesoderm show defects in cell shape as well as multinucleated cells. Gastrulation is delayed.

(Dahlberg et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

CycT^HMS00776, Scer\GAL4^drm.7.1 is a suppressor of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)