FB2025_01 , released February 20, 2025
Allele: Dmel\Nup50HMS01054
Open Close
General Information
Symbol
Dmel\Nup50HMS01054
Species
D. melanogaster
Name
FlyBase ID
FBal0257718
Feature type
allele
Associated gene
Dmel\Nup50
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS01054}
Also Known As
Nup50 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
in vitro construct
(Ni et al., 2010.12.1)
Progenitor genotype
Carried in construct
P{TRiP.HMS01054}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS01054
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Nup50HMS01054 under the control of Scer\GAL4unspecified does not cause significant disruptions in karyosome formation and abnormal chromatin attachment to nuclear periphery in oocytes.

      (Breuer and Ohkura, 2015)

      Expression of Nup50HMS01054 under the control of Scer\GAL4bbg-C96 does not result in any obvious wing phenotype.

      (Ellis et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Nup50HMS01054, Scer\GAL4bbg-C96 is a suppressor of visible phenotype of Scer\GAL4bbg-C96, domRNAi.Sym.UAS

      (Ellis et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Nup50HMS01054, Scer\GAL4bbg-C96 is a suppressor of wing phenotype of Scer\GAL4bbg-C96, domRNAi.Sym.UAS

      (Ellis et al., 2015)
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Nup50HMS01054 suppresses the wing nicking phenotype of flies expressing domdsRNA.Sym.Scer\UAS under the control of Scer\GAL4bbg-C96.

      (Ellis et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Nup50HMS01054
      Name Synonyms
      Secondary FlyBase IDs
        References (5)